NCT06299800
Phenotyping Patients With Type 2 Diabetes Mellitus and Cancer
Recruiting · Not specified · Azienda Ospedaliero Universitaria Maggiore della Carita · registry updated 2026-10-29
Inclusion and exclusion lines below are quoted from ClinicalTrials.gov. No match score is shown, because a score needs a person's age, biomarkers, and treatment dates. Confirm the record with the study team.
Recent research has highlighted the significant relationship between type 2 diabetes mellitus and cancer, both prevalent and impactful on global health. The intrinsic correlation arises from shared metabolic processes, particularly a systemic and chronic inflammatory state driven by factors like obesity, dyslipidemia, and hyperglycemia. This leads to the creation of a self-sustaining microenvironment known as meta-inflammation, promoting cancer development through DNA damage, oxidative stress, and the influence of hormones like leptin. The hyperglycemic environment in diabetes contributes to cancer development, supporting the Warburg effect and insulin-related mechanisms. This study aims to identify risk factors associated with diabetes that impact tumor development and progression, crucial for guiding effective preventive strategies in clinical practice....
Inclusion
- Diagnosis of type 2 diabetes mellitus
Exclusion
- Diagnosis of cancer before diagnosis of type 2 diabetes
- Diagnosis of diabetes secondary to other diseases
- Diagnosis of diabetes secondary to other drugs
- Diagnosis of diabetes following surgery