NCT06526533
RECOMMEND Platform Trial
Recruiting · Phase 3 · Australian and New Zealand Intensive Care Research Centre · registry updated 2026-05-13
Inclusion and exclusion lines below are quoted from ClinicalTrials.gov. No match score is shown, because a score needs a person's age, biomarkers, and treatment dates. Confirm the record with the study team.
The goal of this platform trial is to determine the efficacy, safety and cost-effectiveness of various interventions in patients with acute cardiorespiratory failure requiring extracorporeal membrane oxygenation (ECMO) The main question the platform trial aims to address is to determine the effect of a range of interventions on survival, organ support and resource utilisation to day 28 for hospitalised patients receiving ECMO. Researchers will compare various interventions within multiple platform trial domains to see if the interventions have effects on survival, organ support and resource utilisation for the patient cohort. Participants will be enrolled in accordance with the platform trial's domain structure to answer the research questions.
Inclusion
- Patients receiving ECMO
- Patients enrolled in the EXCEL Registry - NCT03793257
Exclusion
- Treating clinician regards death as imminent and inevitable
- Treating clinician determines it is not in the patient's best interests
- RBC TRANSFUSION DOMAIN INCLUSION CRITERIA:
- Aged 18 years or older
- RBC TRANSFUSION DOMAIN EXCLUSION CRITERIA:
- Contraindication to RBC transfusion (including known patient preference)