NCT07157202
Associating Gastric Infection With Autoimmune Flare Severity in an Egyptians
Not Yet Recruiting · Not specified · Assiut University · registry updated 2025-09-05
Inclusion and exclusion lines below are quoted from ClinicalTrials.gov. No match score is shown, because a score needs a person's age, biomarkers, and treatment dates. Confirm the record with the study team.
A cross-sectional, observational study aims to evaluate the relationship between Helicobacter pylori infection and disease activity in patients diagnosed with systemic lupus erythematosus (SLE), using a combination of structured patient interviews, standardized disease assessments, and laboratory detection of H. pylori by stool antigen testing .
Inclusion
- Adult patients (aged ≥18 years) with a confirmed diagnosis of SLE according to the American College of Rheumatology (ACR) or Systemic Lupus International Collaborating Clinics (SLICC) classification criteria.
- Patients who provide written informed consent to participate in the study. Patients who have not received antibiotics or proton pump inhibitors (PPIs) in the four weeks
Exclusion
- Patients with a history of gastric surgery or known gastrointestinal malignancy.
- Patients currently receiving immunosuppressive therapy for conditions other than SLE.
- Patients with coexisting autoimmune diseases other than SLE.
- Pregnant or lactating women.
- Patients with active infections (other than H. pylori) at the time of enrollment.