NCT07172672
The TiMeD-T1D Project
Not Yet Recruiting · Not Applicable · University of Aarhus · registry updated 2025-09-26
Inclusion and exclusion lines below are quoted from ClinicalTrials.gov. No match score is shown, because a score needs a person's age, biomarkers, and treatment dates. Confirm the record with the study team.
The aim of the proposed study is to investigate the metabolic consequences of varying the timing of meal insulin boluses and skipping boluses altogether in individuals with type 1 diabetes. The investigator hypothesize that delaying or skipping meal insulin boluses leads to greater ectopic fat storage due to a delayed stimulation of lipoprotein activity and delayed suppression of lipolysis and VLDL-TG secretion.
Inclusion
- Type 1 diabetes duration \> 3 years or c-peptide negative
- Written and informed consent
Exclusion
- Medicine with an impact on blood glucose or blood pressure
- Affected screening blood sample as evaluated by the clinical responsible investigator.
- Alcohol or substance abuse
- BMI \> 35 kg/m2 or \< 18.5 kg/m2
- Participation in other clinical trials involving ionized radiation within the last 6 months
- Lactose intolerance