NCT07239479
DEXDES Trial: Dexmedetomidine-Desflurane Combination in Laparoscopic Colectomy
Recruiting · Not Applicable · Tam Anh Research Institute · registry updated 2025-12-30
Inclusion and exclusion lines below are quoted from ClinicalTrials.gov. No match score is shown, because a score needs a person's age, biomarkers, and treatment dates. Confirm the record with the study team.
This randomized double-blind controlled clinical trial aims to evaluate the efficacy and safety of combining Dexmedetomidine with Desflurane in patients undergoing elective laparoscopic colectomy. The study will assess whether the combination can reduce Desflurane consumption, improve intraoperative hemodynamic stability, and enhance postoperative recovery compared to Desflurane alone.
Inclusion
- Age 18-65 years
- ASA Physical Status I-II
- Elective laparoscopic colectomy
- Written informed consent provided
Exclusion
- Severe cardiac, hepatic, or renal disease
- COPD or bronchial asthma
- Chronic opioid or psychotropic medication use
- Atrioventricular block (grade II-III), sick sinus syndrome
- Significant intraoperative bleeding or hemodynamic instability