NCT07290114
Mesh-Free Versus Mesh-Based Surgery for Female Stress Urinary Incontinence: A Prospective Comparison of Pubo-Urethral Ligament Plication and Transobturator Tape
Recruiting · Not Applicable · Mehmet Incebıyik · registry updated 2025-12-18
Inclusion and exclusion lines below are quoted from ClinicalTrials.gov. No match score is shown, because a score needs a person's age, biomarkers, and treatment dates. Confirm the record with the study team.
This prospective clinical study aims to compare the short-term effectiveness, safety, and patient-reported outcomes of two surgical techniques used for the treatment of female stress urinary incontinence (SUI): Pubo-Urethral Ligament Plication (PLP), a mesh-free native tissue repair method, and the Transobturator Tape (TOT) procedure, a commonly used mesh-based mid-urethral sling technique. The study evaluates continence improvement, perioperative and postoperative complications, operative time, hospital stay, postoperative pain, and patient satisfaction. The goal is to provide evidence on whether a mesh-free surgical option such as PLP can offer comparable outcomes to mesh-based TOT, particularly for patients seeking alternatives to synthetic materials.
Inclusion
- Female patients aged 18-80 years
- Clinical diagnosis of stress urinary incontinence
- Failure of conservative management (pelvic floor exercises or medical therapy)
- Desire to undergo surgical treatment (PLP or TOT)
- Ability to provide informed consent
- Willingness to attend postoperative follow-up visits
Exclusion
- Mixed urinary incontinence with predominant urge symptoms
- Active urinary tract infection
- Pelvic organ prolapse ≥ stage II
- Previous anti-incontinence surgery
- Neurological diseases affecting bladder function
- Pregnancy or planning pregnancy during follow-up