NCT07630194
Occupation-Based Cognitive Stimulation With and Without Motivational Feedback in Parkinson's Disease
Not Yet Recruiting · Not Applicable · University of Nevada, Las Vegas · registry updated 2026-10-01
Inclusion and exclusion lines below are quoted from ClinicalTrials.gov. No match score is shown, because a score needs a person's age, biomarkers, and treatment dates. Confirm the record with the study team.
Background: Cognitive impairment and psychological symptoms are highly prevalent in Parkinson's disease (PD) and significantly compromise daily functioning and quality of life. Occupation-based cognitive stimulation may enhance ecological validity and engagement, while motivational feedback could further improve adherence and neuroplasticity. However, the combined effects of these approaches have not been systematically examined in PD. Objective: To evaluate the effects of enjoyable occupation-based cognitive stimulation with and without motivational feedback on cognitive, psychological, and occupational outcomes in older adults with PD and cognitive impairment. Methods: This single-blind, three-arm randomized controlled trial will enroll 71 community-dwelling older adults with idiopathic PD. Participants will be randomly assigned to: (A) occupation-based cognitive stimulation with motivational feedback, (B) occupation-based cognitive stimulation without motivational feedback, or (C) gold standard of conventional occupational therapy. Interventions will consist of 12 supervised sessions over 6 weeks....
Inclusion
- Idiopathic Parkinson's disease (PD) diagnosed according to the UK Parkinson's Disease Society Brain Bank criteria
- Aged 60-80 years
- Classified as Hoehn and Yahr stages I-IV
- Mild-to-moderate cognitive impairment, defined as a Montreal Cognitive Assessment (MoCA) score of 21-25
- Able to complete self-report measures
Exclusion
- History of impulsive-compulsive disorders, confirmed through neurologist-led clinical interviews
- atypical parkinsonian syndromes, coexisting neurological disorders (e.g., stroke, other neurodegenerative diseases)
- Young-onset PD