NCT07774507
Twenty-four Hour Movement Behaviors and Atherosclerotic Risk
Recruiting · Not specified · São Paulo State University · registry updated 2026-08-20
Inclusion and exclusion lines below are quoted from ClinicalTrials.gov. No match score is shown, because a score needs a person's age, biomarkers, and treatment dates. Confirm the record with the study team.
This observational study aims to investigate how 24-hour movement behaviors are associated with atherosclerotic risk in adults with rheumatoid arthritis. These behaviors include physical activity, sedentary behavior, and sleep. The main questions it aims to answer are: * Are 24-hour movement behaviors, both individually and in combination, associated with indicators of atherosclerotic risk in adults with RA? * Do changes in 24-hour movement behaviors over 12 months relate to changes in indicators of atherosclerotic risk? Participants will: * Wear activity monitors (accelerometers) continuously for 7 days to measure physical activity, sedentary behavior, and sleep. * Answer questionnaires about their health and lifestyle. * Undergo cardiovascular assessments, body composition measurements, physical fitness tests, and blood tests to measure lipid and inflammatory profile. * Return 12 months later for follow-up assessments. The researchers hope this study will improve understanding of how daily movement behaviors influence cardiovascular health in people with rheumatoid arthritis....
Inclusion
- Medical diagnosis of rheumatoid arthritis.
- Age between 18 and 65 years.
- Provide written informed consent.
- Independence in daily living activities defined as a Katz Index score of 5 or 6 points.
Exclusion
- Acute infectious disease at the time of assessment.
- Pregnancy or breastfeeding.
- Cognitive impairment identified by the Mini-Mental State Examination according to established cutoff values.
- History of cardiovascular disease, including coronary artery disease, cerebrovascular disease, peripheral arterial disease, rheumatic heart disease, congenital heart disease, deep vein thrombosis, or pulmonary embolism.
- Use of uncontrolled vasoactive medication.
- Inability to comply with accelerometer wear requirements.