NCT07847983
Heart Failure in Women: Epidemiological and Prognostic Insights
Recruiting · Not specified · Carolina Ortiz Cortes · registry updated 2026-10-21
Inclusion and exclusion lines below are quoted from ClinicalTrials.gov. No match score is shown, because a score needs a person's age, biomarkers, and treatment dates. Confirm the record with the study team.
Heart failure (HF) is a leading cause of hospital admission in older adults and women account for more than half of these admissions, yet they remain under-represented in prospective HF cohorts. Risk factors specific to women, such as complications of pregnancy and the timing of menopause, are seldom recorded in HF registries, and treatment is usually described by drug class rather than by the dose actually achieved. HER-HF is a national, prospective, multicenter observational cohort study that enrolls women aged 18 years or older admitted to hospital for a first episode of HF, irrespective of left ventricular ejection fraction, at 24 Spanish hospitals with a dedicated heart failure unit. Recruitment is consecutive and all-comers. Participants are enrolled at discharge from the index admission or at the first heart failure unit visit within 15 days, and all baseline data refer to the index hospitalization. Participants are followed for 12 months, with visits at 3, 6 and 12 months. The primary objective is descriptive: to characterize the epidemiological, clinical, diagnostic, therapeutic and prognostic profile of women with de novo HF, from the index admission through 12 months....
Inclusion
- Women aged 18 years or older.
- Hospital admission with a first episode of heart failure confirmed by the treating team according to current clinical practice guidelines, irrespective of left ventricular ejection fraction.
- Written informed consent given by the participant after verbal and written information.
Exclusion
- Total functional dependence, defined as a Barthel index score of 20 or less (0-100 version).
- Moderate-to-severe cognitive impairment, defined as 5 or more errors on the Pfeiffer questionnaire, adjusted for educational attainment.
- Severe frailty, defined as a Clinical Frailty Scale score of 6 or more.
- Terminal illness unrelated to heart failure with an expected survival of less than 6 months according to clinical judgment.
- Inability to complete clinical follow-up or subsequent contact (for example, no contact details available, or transfer to a center outside the network).
- Any previous diagnosis of heart failure.